“My brain has way too many tabs open.”
“Why can’t I complete tasks?”
“Why do I lose track of time?”
“Why can’t I pay attention?”
These are all things people with attention-deficit/hyperactivity disorder, or ADHD, may ask themselves daily, if not hourly.
As a , I have diagnosed and treated numerous patients with ADHD. I was also diagnosed with it at the age of 21.
Understanding how the wiring differs in a brain with ADHD and what improves functioning is critical to help those struggling because of their brain’s uniqueness.
How brains with ADHD differ
Research has identified multiple differences .
Put simply, ADHD significantly affects executive function.
is a set of cognitive processes, including planning, prioritizing, impulse control, flexibility, time management and emotional regulation, that help people achieve long-term goals.
These processes – the “personality center” – of the brain.
In addition to the prefrontal cortex, ADHD affects other areas of the brain, including the , an area that regulates communication within the brain, and the , which is responsible for movement and balance. All three work together regulating attention, and .
Chemical messengers called neurotransmitters allow brain cells to communicate with each other. and are two key neurotransmitters that play critical roles in the .
Dopamine controls . We get a flood of dopamine from pleasurable things such as eating, drinking alcohol, having sex, and receiving affirmations or good grades. That flood also motivates us to repeat the “rewarding” behavior. Norepinephrine is responsible for .
People with ADHD and in brain regions, including the prefrontal cortex. This leads to difficulty in sustaining cognitive functions such as attention, .
Studies show that people with ADHD have . Think of transporters as vacuums that suck dopamine back up into the neuron, making it less available.
As a result, there is in the prefrontal cortex and , the area that processes rewards and motivation. Less dopamine can drive people to seek out stimulating rewards such as technology, food or drugs.
Researchers have identified at least 27 possible genetic markers that .
Diagnosing ADHD
Nearly everyone with or without ADHD show some symptoms such as forgetfulness. For instance, when you can’t tolerate sitting in a meeting for one moment longer or you can’t remember why you came into a room.
A true ADHD .
If you struggle with ADHD, you have in the inattentive, hyperactive or impulsive categories, such as forgetfulness, trouble sitting still, losing items and getting easily distracted.
For a formal diagnosis, ADHD symptoms need to have been present before the age of 12, something that can be determined in childhood or, as in my case, much later.
Also, ADHD symptoms must negatively affect the person , such as at home, in school or at work – and they can’t be explained away by other conditions, such as .
Research shows that girls with ADHD more often along with characteristics not traditionally associated with ADHD, such as and . Patients, , can develop depression or anxiety – or both – because of untreated ADHD. Once ADHD is treated, anxiety and depression symptoms .
How ADHD medications alter neurotransmitters
The American Academy of Pediatrics provides for the treatment of ADHD in children and teens.
The first U.S. guidelines for the treatment of adult ADHD are expected to be .
If patients are 6 or older, stimulant or nonstimulant medications may be used, along with behavioral therapy.
Stimulants are divided into two drug classes: amphetamines, such as Adderall and Vyvanse, and methylphenidates, such as Concerta, Ritalin and Focalin.
Nonstimulants such as Strattera are recommended if patients cannot tolerate or prefer not to take stimulant medications.
Stimulants and , preventing them from depleting those neurotransmitters, so more dopamine is available to activate key areas of the brain.
Amphetamines also increase the release of . These increased levels allow the brain to find challenging tasks, such as doing homework, more rewarding. Because more dopamine is available, the brain’s desire for stimulating rewards decreases.
Methylphenidates are typically the , while amphetamines are most effective in adults.
have found that stimulants , , parental quality of life and behavioral ratings from teachers. Stimulants and . Nonstimulants also .
Improved outcomes
People with ADHD attempt suicide at . They also have three times the rate of suicidal ideation and .
Treating patients with ADHD with stimulant medication, in addition to behavioral therapy, has been shown to , and . One study found that treating children with ADHD with methylphenidate .
In addition to medication, , , , and have been shown to be effective for ADHD symptoms. Most researchers agree that behavioral training is most effective when .
Positive parenting
Research has found significant improvement in the when parents . The effect is even more pronounced when .
One such model, called the ,” has been used , , and , including the . It emphasizes praise and encouragement, the setting of clear boundaries for acceptable behavior, and teaches children to self-regulate emotions and behaviors.
As a medical provider, I have witnessed such models work wonders in families and classrooms.
Dietary supplements
Multiple studies have demonstrated that children with ADHD have in their bloodstream.
Having adequate iron in one’s body, stored in the protein , is important to create , the neurotransmitters that are lacking in ADHD. Research has demonstrated that . Children with .
For this reason, it’s important for providers to check ferritin levels and not serum iron, which is often used incorrectly to diagnose .
Taking steps forward
If you think your child or you may have ADHD, speak with a health care provider who is familiar with ADHD treatment. For school accommodations, the first place to start is with your provider.
Research is still ongoing, but high intake of processed foods may worsen .
Pay attention to sleep; and are common in people with ADHD.
And make sure to get in lots of exercise, because it while boosting dopamine and norepinephrine levels.
Though overwhelming, I’m happy to say that living with ADHD can be rewarding.
: We are resilient, unconventional and creative. We have intense energy that, once harnessed, can be used for incredible good.