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Collaboration advancing medical research: Drs Anna Waterhouse and John O’Sullivan

Collaboration is essential to advancing medical research, so HRI are delighted that Drs Anna Waterhouse and John O’Sullivan and their multiple research collaborations are featured by the Charles Perkins Centre, The University of Sydney.

Dr Anna Waterhouse

, originally from the UK, is Group Leader at HRI and senior lecturer at The University of Sydney’s Central Clinical School. Her research focuses on generating new materials, surface coatings and ultimately, new medical devices. Her work, conducted at HRI headquarters and the Charles Perkins Centre at The University of Sydney, aims to improve and develop new medical devices and diagnostics.

“It was really the opportunity to continue to do multidisciplinary research and be in an environment where people with different backgrounds and training can come together to solve global healthcare problems,” Dr Waterhouse says, on choosing to bring her research to HRI and the Charles Perkins Centre.

“It’s very easy to work with group leaders and set up collaborations as well as access to the Royal Prince Alfred Hospital (RPA), because of the location. So we are able to talk to clinicians and again build research collaborations, which ultimately lead to some fantastic discoveries.”

Dr Waterhouse is engaged in two exciting multidisciplinary projects on nano coatings and DNA nano robots to improve cardiovascular health.

Dr John O’Sullivan

For cardiologist and scientist , his research and clinical work is made possible by meaningful and long-lasting collaborations. As Group Leader at HRI and The University of Sydney’s Charles Perkins Centre, a senior lecturer at the University’s Central Clinical School and Sydney Medical School, as well as a cardiologist at RPA, Dr O’Sullivan is able to take a global approach to solving the issues that come from cardiometabolic disease.

Originally from Ireland, Dr O’Sullivan’s research focuses on cardiometabolic health, and the link between metabolic disease and cardiovascular disease, particularly heart failure.

“I fulfil my mission in world-class facilities,” Dr O’Sullivan says. ​”It is all possible because of the local clinical and research expertise here and in the Local Health District, including the metabolomics, clinic, availability of fresh heart tissue, and the heart bank. My collaborators at the centre enhance my research by providing allied expertise in closely related fields.”

A collaboration between Dr O’Sullivan and Dr Waterhouse has enabled Dr O’Sullivan to continue his research into stiff heart failure using fresh heart tissue, due to Dr Waterhouse’s invention of a 3-D printed device that keeps the heart tissue slices alive and allows modelling of the pumping.

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