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Low-Cost Liquid Tames Tooth Decay

Silver diamine fluoride prevents cavities and keeps existing ones from worsening in school-based program

Small vial of silver diamine fluoride

The cavity-fighting liquid silver diamine fluoride (SDF) kept tooth decay at bay in a school program.

An inexpensive, cavity-fighting liquid called silver diamine fluoride (SDF) works as well as dental sealants to keep tooth decay at bay in a school cavity prevention and treatment program, according to a new study by researchers at NYU College of Dentistry.

The study, which followed more than 4,000 elementary school students for four years and is , shows that SDF is an effective alternative to sealants, and can increase access to dental care while reducing costs.

Dental cavities are and can lead to pain, school absences, and lower academic performance. To prevent cavities, especially among children less likely to see a dentist, the . In sealant programs, dental professionals visit schools to apply a thin, protective coating to the surface of teeth that hardens and safeguards against decay.

has emerged as another promising treatment for fighting cavities. Originally approved by the FDA for treating tooth sensitivity, the solution is brushed onto the surface of teeth, killing decay-causing bacteria and remineralizing teeth to prevent further decay.

“A growing body of research shows that SDF-which is quicker to apply and less expensive than sealants-can prevent and arrest cavities, reducing the need for drilling and filling,” said , professor of epidemiology & health promotion at NYU College of Dentistry and the study’s senior author.

oral health professionals in school-based program

CariedAway, the nation’s largest school-based cavity prevention study, in a Bronx elementary school. © Sorel: NYU Photo Bureau

SDF in schools

Researchers at NYU College of Dentistry led CariedAway, the nation’s largest school-based cavity prevention study, to compare the use of SDF and traditional sealants. The study included approximately 4,100 children in New York City elementary schools; more than a quarter of kids had untreated cavities at the start of the study.

At each school visit, a team of health professionals examined children’s teeth and applied either sealants or SDF followed by fluoride varnish, depending on which treatment the school was randomly assigned to receive. Sealants were administered by dental hygienists, while SDF was applied by either dental hygienists or registered nurses, all under the supervision of a dentist. Starting in 2018, the team visited each school twice a year, although the COVID-19 pandemic and school closures led to missed visits.

The researchers that a single treatment of either SDF or sealants prevented 80% of cavities and kept 50% of existing cavities from worsening two years later. The team continued their study for another two years, and in their study published in JAMA Pediatrics, found that SDF and sealants prevented roughly the same number of cavities after children were followed for a total of four years. Moreover, both sealants and SDF reduced the risk of decay at each follow-up visit.

“Our longitudinal study reaffirms that both sealants and SDF are effective against cavities. SDF is a promising alternative that can support school-based cavity prevention-not to replace the dental sealant model, but as another option that also prevents and arrests decay,” said , associate professor of epidemiology & health promotion at NYU College of Dentistry and the study’s first author.

“Most research shows that SDF can stop a cavity from progressing further. Our study demonstrated that SDF can prevent cavities from happening in the first place,” said Tamarinda Barry Godín, DDS, MPH, associate program director and supervising dentist for CariedAway, research scientist at NYU College of Dentistry, and the study’s coauthor.

Oral health professionals in a Bronx elementary school

SDF prevented and treated cavities as well as sealants in the school-based program. © Sorel: NYU Photo Bureau

An “untapped” oral health workforce

Embracing SDF for cavity prevention and treatment in schools could keep kids from needing fillings, saving families and the healthcare system money. Yet these programs can only succeed if there are enough health professionals to provide care.

The NYU researchers found that children who had SDF applied by dental hygienists and registered nurses had similar outcomes, suggesting that nurses-including school nurses-could play a crucial role in cavity prevention programs.

“Nurses may be an untapped resource for addressing oral health inequities,” added Ruff. “Our results suggest that nurses can effectively provide this preventive care, which could dramatically improve access, given the role of school nurses and the size of the nursing workforce.”

This research was funded by the Patient-Centered Outcomes Research Institute (PCS-160936724). The CariedAway cavity prevention model is currently being used in three New Hampshire school districts, supported by Northeast Delta Dental.

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