Police have arrested a man and a woman following a pursuit in Diggers Rest this afternoon.
It is understood the pair in a white Camry were travelling along Plumpton Road when they allegedly got into an altercation with the driver of a Volkswagen Golf, about 2.25pm.
The male passenger of the Camry allegedly threatened the Volkswagen driver with a firearm before they fled towards Taylors Road.
Officers quickly responded to the incident and initiated a pursuit.
The offending driver allegedly conducted a U-turn heading south on Taylors Road, narrowly missing one of the police vehicles.
The pursuit continued towards the intersection of Leakes Road, where the driver allegedly overtook multiple vehicles and ran a red light.
Officers successfully deployed stop sticks and the driver lost control, narrowly missing another vehicle and hitting a tree on the other side of the road.
The impact forced the car to roll several times, ejecting the male passenger from the vehicle.
The 32-year-old St Albans driver and her 35-year-old Taylors Lakes passenger sustained non-life-threatening injuries and were taken to hospital under police guard.
The exact cause of the collision is yet to be determined and investigations remain ongoing.
Anyone who witnessed the incident or has information is urged to contact Crime Stoppers on 1800 333 000 or submit a confidential report online at www.crimestoppersvic.com.au